SARS; Research finds feces may be key in spreading virus

来源:公共卫生突发事件咨询服务与研究中心  作者:  发布时间:2003-06-04  查看次数:1017

Abstract:
The report was among several new findings. One study found that the SARS virus can live on chilled surfaces like those in a refrigerator for as long as 4 days. Another found common disinfectants can kill the virus.

Full Text:
Copyright 2003, Medical Letter on the CDC & FDA via NewsRx.com &NewsRx.net

2003 JUN 1 - (NewsRx.com & NewsRx.net) -- New scientific findings indicate that feces may be a more important method of spreading the SARS virus than originally thought, the World Health Organization (WHO) says.

Although coughing and sneezing remain the chief means of spreading the infection, government scientists in Hong Kong have found that the virus can stay alive for at least 4 days in diarrhea.

The research adds weight to the theory that leaky sewage pipes were the source of infection in a particularly severe outbreak at a Hong Kong apartment complex, where more than 300 people became ill.

The report was among several new findings. One study found that the SARS virus can live on chilled surfaces like those in a refrigerator for as long as 4 days. Another found common disinfectants can kill the virus.

Two doctors from the WHO arrived in Taiwan May 4 to help the island cope with its worsening SARS outbreak, after China's government put aside politics and agreed to the visit.

Dr. Klaus Stohr, the WHO's chief SARS scientist, said discovery that the virus can survive in feces at room temperature for as long as 4 days was "the most exciting, or perhaps disturbing, finding."

He said diarrhea provides a more favorable environment for the virus as the stool in that condition is less acidic.

Although only about 10% of people stricken with severe acute respiratory syndrome get diarrhea, the rate among patients infected in the Amoy Gardens apartment complex was 60%.

"That finding is the most disturbing one because it would suggest that fecal-oral transmission could take place," said Stohr, who was not directly involved in the research but coordinates the work of labs around the world investigating the SARS virus.

In another experiment, Stohr said, Hong Kong University scientists confirmed that common disinfectants can kill the virus in 5 minutes.

"The good news from these findings is that the virus can be relatively easily killed with common disinfectants," he said. The Hong Kong scientists found that formaldehyde, ethanol and acetone, three common disinfectants, kill the virus.

Disinfecting toilets in hospitals and homes where people have had contact with SARS would likely solve the problem, he said.

Stohr said that in an ongoing study, Japanese researchers had found that the SARS virus had so far stayed alive for 4 days in cells on plastic surfaces at a temperature of 40 degrees.

"This is fridge temperature, so if someone touches something with a SARS contaminated hand, it would stay for 4 days on something in the fridge," Stohr said.

The virus was also tested at -112 degrees for 4 days and it was unaffected. But this was no surprise, Stohr said, because many viruses survive easily in cold temperatures.

It was already clear that the SARS virus can survive winter. The outbreak began in November in China and survived the winter there to spread farther afield in the spring.

This article was prepared by Medical Letter on the CDC & FDA editors from staff and other reports.