新一期美国《中风》杂志刊登一份瑞典研究报告说，每天喝超过一杯咖啡的女性中风的几率明显低于不经常喝咖啡的女性。
瑞典卡罗琳医学院研究人员报告说，他们对超过3．4万名49岁至83岁的女性进行了大约10年的跟踪调查。其间共有1680名女性患中风，其中205名女性喝咖啡的量少于每天一杯。分析显示，与根本不喝咖啡或每天喝少于一杯咖啡的女性相比，每天喝超过一杯咖啡的女性患中风的几率要低22％至25％。
领导研究的苏珊娜·拉松说，这项研究考虑了吸烟、饮酒、体重以及是否患慢性病等其他风险因素的影响。研究表明，常喝咖啡能起到降低中风风险的效果。但也不需要喝太多，每天一至两杯足够。
研究人员强调，相关研究有待进一步深入，以弄清喝咖啡降低中风风险的机理，那些不喝咖啡的人没有必要因为这项结果而立刻改变习惯。
Coffee Consumption and Risk of Stroke in Women
Susanna C. Larsson, PhD; Jarmo Virtamo, MD; Alicja Wolk, DMSc
Abstract
Background and Purpose—Coffee consumption has been inconsistently associated with stroke incidence and mortality in previous studies. We investigated the association between coffee consumption and stroke incidence in the Swedish Mammography Cohort.
Methods—We prospectively followed of 34 670 women without a history of cardiovascular disease or cancer at baseline in 1997. Coffee consumption was assessed in 1997 using a self-administered questionnaire. Incident stroke cases were ascertained from the Swedish Hospital Discharge Registry.
Results—During a mean follow-up of 10.4 years, we ascertained 1680 stroke events, including 1310 cerebral infarctions, 154 intracerebral hemorrhages, 79 subarachnoid hemorrhages, and 137 unspecified strokes. After adjustment for other risk factors, coffee consumption was associated with a statistically significant lower risk of total stroke, cerebral infarction, and subarachnoid hemorrhage but not intracerebral hemorrhage. The multivariable relative risks of total stroke across categories of coffee consumption (<1 cup/day, 1 to 2 cups/day, 3 to 4 cups/day, and 5 cups/day) were 1.00, 0.78 (95% CI, 0.66 to 0.91), 0.75 (95% CI, 0.64 to 0.88), and 0.77 (95% CI, 0.63 to 0.92, respectively; P for trend=0.02). The association between coffee consumption and cerebral infarction was not modified by smoking status, body mass index, history of diabetes or hypertension, or alcohol consumption.
Conclusions—These findings suggest that low or no coffee consumption is associated with an increased risk of stroke in women.
